SIAMG 2025| Precision Decoded with ClairLabs

Bridging The Gap from Sequencers to Clinical Leaders

At Pune, we promised to simplify complexity, and we did. Introducing Impactomics, our AI-genomics platform. Built on the ML variant ranking method, labs now achieve validated 98% pathogenic-variant ranking accuracy, while cutting reporting time in half. That’s not incremental improvement — it’s a new operational baseline for clinical genomics.

The trade-off between speed and accuracy is over. Impactomics turns FASTQ into clinician-ready, audit-grade reports at cloud scale, so diagnostic teams stop firefighting and start delivering faster, measurable patient impact.

Key Takeaways from SIAMG 2025

Agentic AI: The New Digital Workforce

Our showcase highlighted how autonomous agents actively troubleshoot pipeline failures, coach lab staff on new protocols, and explain complex variant evidence in real time. Explore how to transform QC, training, and review into automated, auditable workflows.

Nurturing an API-first culture

We design robust integrations so product & engineering teams can securely connect a genomics API to healthcare apps, enable seamless sample tracking, and integrate with LIMS/EHR (FHIR/HL7) without compromising compliance. Deploy ML for early-stage cancer detection or a transparent pricing model for genomics API providers.

Heart of The Matter

Impactomics shifts genomics from a cost center to a business driver: faster TAT, lower OPEX, higher diagnostic yield, and data products you can monetize. We help labs scale from pilot to 100K+ samples while keeping regulators and clinicians confident.

Setting The New Standard for Germline Interpretation

Impactomics elevates NGS diagnostic accuracy by pairing phenotype-aware AI with validated ML ranking and automated ACMG classification. Result? Geneticists see the right candidates faster and with auditable evidence.

The Vantage Point

ML-ranked accuracy

Effectively ranks pathogenic variants with validated top 10 accuracy (98%) for rare and inherited disease cohorts.

Automated ACMG

AutoACMG applies guideline-based evidence mapping for consistent, reproducible classifications.

Phenotype-driven insight

Integrated HPO extraction and phenotype-matching focus review on clinically relevant genes.

From Our Thought Leaders’ Desk

Reimagining Rare Disease Diagnosis with Gen AI: ClairLabs’ Vision for the Future of Precision Medicine

Rare diseases account for nearly 5% of the global disease burden. With the advent of novel technologies such as AI, Gen AI, NLP, and augmented reality, debates and discussions around

From Silos to Seamless: How API-first Ecosystems are Redefining Genomics & Healthcare IT

The success metrics for genomics and healthcare IT projects have undergone significant changes in the past few years. Healthcare leaders are moving away from traditional single-point-of-care monolithic solutions toward more intuitive

Multi-omics-led Tech Consulting in the Age of Generative Biology: Modernizing Labs for Building Foundation-scale Models

Looking back a decade ago, it’s amusing how we were all fascinated by J.A.R.V.I.S. in the movie Iron Man, an NLP-based interface developed by the protagonist Tony Stark. It could retrieve real-time medical images

We Didn’t Just Predict
the Autonomous Lab
We Built It at SIAMG 2025, Pune

Bridging The Gap from Sequencers to Clinical Leaders

Key Takeaways from SIAMG 2025

Setting The New Standard for Germline Interpretation

The Impactomics Technical Blueprint

From Our Thought Leaders’ Desk

We Didn’t Just Predict the Autonomous Lab We Built It at SIAMG 2025, Pune

Bridging The Gap from Sequencers to Clinical Leaders

Key Takeaways from SIAMG 2025

Setting The New Standard for Germline Interpretation

The Impactomics Technical Blueprint

From Our Thought Leaders’ Desk

We Didn’t Just Predict
the Autonomous Lab
We Built It at SIAMG 2025, Pune